3-(chloromethyl)-4-[(4-hydroxyphenyl)methylidene]-1,2-oxazol-5-one
(4E)-3-(Chloromethyl)-4-(4-hydroxybenzylidene)-isoxazol-5(4H)-one
CAS: 1142199-72-1
Molecular Formula: C11H8ClNO3
3-(chloromethyl)-4-[(4-hydroxyphenyl)methylidene]-1,2-oxazol-5-one - Names and Identifiers
3-(chloromethyl)-4-[(4-hydroxyphenyl)methylidene]-1,2-oxazol-5-one - Physico-chemical Properties
| Molecular Formula | C11H8ClNO3 |
| Molar Mass | 237.64 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD12027823 |
3-(chloromethyl)-4-[(4-hydroxyphenyl)methylidene]-1,2-oxazol-5-one - Risk and Safety
| Hazard Class | IRRITANT |
3-(chloromethyl)-4-[(4-hydroxyphenyl)methylidene]-1,2-oxazol-5-one - Introduction
(4E)-3-(Chloromethyl)-4-(4-hydroxybenzylidene)-isoxazol-5(4H)-one, chemical formula C12H9ClN2O2, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: It is a white crystalline solid.
-Solubility: It is difficult to dissolve in solvents, such as almost insoluble in water.
-Melting point: about 166-168 ℃.
Use:
- (4E)-3-(Chloromethyl)-4-(4-hydroxybenzylidene)-isoxazol-5(4H)-one is an important intermediate, which is widely used in the synthesis of drugs and pesticides.
-In the field of medicine, it is often used to synthesize various biologically active compounds, such as drugs with antibacterial, anti-cancer, anti-diabetes and other effects.
-In the field of pesticides, it can be used for synthetic pesticides and herbicides.
Preparation Method:
The preparation method of- (4E)-3-(Chloromethyl)-4-(4-hydroxybenzylidene)-isoxazol-5(4H)-one can first prepare 4-hydroxybenzylidene formaldehyde by reaction, and then carry out condensation reaction with furanone under acid catalysis to obtain the target product.
Safety Information:
- (4E)-3-(Chloromethyl)-4-(4-hydroxybenzylidene)-isoxazol-5(4H)-one failed to find clear toxicity and hazard assessment information. Please follow relevant safety during operation and use. Operating procedures, avoid direct contact with skin and eyes, pay attention to protective measures, and comply with relevant regulations. When used in the laboratory, follow the chemical safety regulations and follow the instructions on the packaging label and safety data sheet.
Nature:
-Appearance: It is a white crystalline solid.
-Solubility: It is difficult to dissolve in solvents, such as almost insoluble in water.
-Melting point: about 166-168 ℃.
Use:
- (4E)-3-(Chloromethyl)-4-(4-hydroxybenzylidene)-isoxazol-5(4H)-one is an important intermediate, which is widely used in the synthesis of drugs and pesticides.
-In the field of medicine, it is often used to synthesize various biologically active compounds, such as drugs with antibacterial, anti-cancer, anti-diabetes and other effects.
-In the field of pesticides, it can be used for synthetic pesticides and herbicides.
Preparation Method:
The preparation method of- (4E)-3-(Chloromethyl)-4-(4-hydroxybenzylidene)-isoxazol-5(4H)-one can first prepare 4-hydroxybenzylidene formaldehyde by reaction, and then carry out condensation reaction with furanone under acid catalysis to obtain the target product.
Safety Information:
- (4E)-3-(Chloromethyl)-4-(4-hydroxybenzylidene)-isoxazol-5(4H)-one failed to find clear toxicity and hazard assessment information. Please follow relevant safety during operation and use. Operating procedures, avoid direct contact with skin and eyes, pay attention to protective measures, and comply with relevant regulations. When used in the laboratory, follow the chemical safety regulations and follow the instructions on the packaging label and safety data sheet.
Last Update：2024-04-09 02:00:56
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